Koordinatör

Dr. Yeşim Soyer

Office Tel:+90 312 210 5633

Fax: :+90 312 210 2767

E-mail:ysoyer@metu.edu.tr

Araştırma Tecrübesi:

Haziran 2018- Biyokimya Bölüm Başkanı, Orta Doğu Teknik Üniversitesi, Ankara-Türkiye

Mart 2017- Doç. Dr.,  Gıda Mühendisliği, Orta Doğu Teknik Üniversitesi, Ankara-Türkiye

Nisan 2011- Mart 2017, Yrd. Doç. Dr., Gıda Mühendisliği, Orta Doğu Teknik Üniversitesi, Ankara-Türkiye

Haziran 2010- Nisan 2011, Yrd. Doç. Dr., Gıda Mühendisliğ, Harran Üniversitesi Şanliurfa-Türkiye

Eylül 2009-Haziran 2010, Araştırma Görevlisi, Gıda Mühendisliğ, Harran Üniversitesi Şanliurfa-Türkiye

Nisan 2009-Ağustos 2009 Doktora Sonrası Araştırmacı- Cornell Üniversitesi Gıda  Bilimi Bölümünde 

Ağustos 2004- Nisan 2009 Araştırma Görevlisi- Cornell Üniversitesi Gıda Bilimi Bölümünde. Doktora Tezi “Evolution and Transmission of Salmonella”. 

• Belli başlı gıda kaynaklı patojenlerin, özellikle Salmonella  ve Listeria monocytogenes’nin, moleküler tekniklerle (örneğin: vuruşlu alan jel elektroforezi, PFGE;çoklu lokus sekanslama tiplemesi, MLST ve microarray)  ve biyoinformatik araçlar kullanılarak tiplenmesi ve insan ve hayvan izolatlarının epidemiyolojik esaslar çevresinde karşılaştırılması. Bu alandaki deneyimim farklı üretim koşullarında gıda kaynaklı hastalıkların iletimini öncelikle anlamak, sonra da engellemek üzerinedir. Böylece patojenlerin çiflikten insana giden aktarım zinciri kırılmış olacaktır. 

• Genotipik analizler (PAML, Phylogenetic Analysis by Maximum Likelihood ve GENECONV, Gene Conversion Statistical Tests for detecting Gene Conversion) ile Salmonella’nın evrimine ışık tutulması  ve pozitif seleksiyonundaki ve/veya rekombinasyona sahip genlerin tespit edilmesi

• Son yıllarda yaygın olarak ABD’de ve Avrupada salgınlara neden olan Salmonella serotip 4,5,12:i:-  ile tüm dünyada salgınlara neden olan Salmonella serotip Typhimurium arasındaki evrimsel ilişkinin tespit edilmesi 

2001-2004 Doktora Öğrencisi, Ankara Üniversitesi Gıda Mühendisliği Bölümü. Meyvelerde antioksidan aktıvıte ve fenoliklerin bağlantısının belirlenmesi. Yeşil bezelyelerde klorofil degradasyon kinetiğinin belirlenmesi

1999-2001 Yüksek Lisans Öğrencisi

Ankara Üniversitesi Gıda Mühendisliği Bölümü, Yüksek Lisans Tezi: ‘Beyaz Üzüm ve sularında organik asitlerin belirlenmesi’

Ödüller ve Burslar:

2015 ODTÜ Mühendislik Fakültesi İlk %20 Başarı Dilimi Ödülü, ORTA DOGU TEKNIK ÜNIVERSITESI, 2014

2007- Nisan 2009 Araştırma Görevlisi, Cornell Üniversitesi Gıda Bilimi

Bölümü

2008 The Eastern NY Branch of The American Society for Microbiology (ASM) Travel Award 

2007-2008 Ruth Herzog and Albert Flegenheimer Graduate Award in Food Science” for academic excellence in Field of Food Science and Technology, Cornell University 

2007 Recipient, Institute of Food Technologists (IFT) NY Section National Fellowship for outstanding graduate students

2004-2006 Yüksek Öğretim Kurulu (YÖK) bursu, ABD’de doktora eğitimi için

2006-2008 Cornell University Graduate School Travel Grant

2005-2008 Cornell University Department of Food Science Travel Grant

2002 Ministry of Foreign Affairs of Israel (MASHAV) Scholarship to attend “The 4th International Post-Graduate Course on Food Technology” Hebrew University of Jerusalem, Rehovat - Israel

Hakemli Degilerdeki Yayınlar:

1. Soyer, Y., Koca, N. and Karadeniz, F. 2003. Organic acid profile of white grapes and grape juices. Journal of Food Composition and Analysis , 16; 629-636.

2. Soyer, Y., Karadeniz, F. and Ekşi, A. 2003. Şeftali pulpındaki organic asit dağılımı. Dünya Gıda , 2003-6; 60-63.

3. Soyer, Y. ve Karadeniz, F. 2003. Gıda Endüstrisindekie Alginatlar. Dünya Gıda , 2003-10; 81-86 (derleme).

4. Karadeniz, F., Burdurlu, H., Koca, N. and Soyer, Y. 2005.  Antioxidant activity of some fruits and vegetables. Turkish-Journal-of-Agriculture-and-Forestry, 29(4): 297-303.

5. Alcaine, S. D., Y. Soyer, L. D. Warnick, W.-L. Su, S. S. Sukhnanand, J.Richards, E. D. Fortes, P. McDonough, T. P. Root, N. B. Dumas, Y.Gröhn, and M. Wiedmann. 2006. Multilocus sequence typing supports the hypothesis that cattle and human associated Salmonella isolates represent distinct and overlapping populations. Applied and Environmental Microbiology 72 (12); 7575-7585.

6. Davis, M. A.,  T.E. Besser, K. Eckmann,  J.K. MacDonald, D. Green, D.D. Hancock, K.N.K. Baker, L.D. Warnick, Y. Soyer, M. Wiedmann and D.R. Call. 2007. Emerging multi-drug resistant strain of Salmonella enterica serovar Typhimurium in the Pacific Northwest United States. Emerging Infectious Diseases 13 (10); 1583- 1586.

7. Döpfer, D., W. Buist, Y. Soyer, M. A. Munoz, R. N. Zadoks, L. Geue and B. Engel. 2007. Assessing Genetic Heterogeneity Within Bacterial Species Isolated From Gastro-Intestinal And Environmental Samples: How Many Isolates Does It Take? Applied and Environmental Microbiology 74 (11); 3490–3496.

8. Erge, H.S., F. Karadeniz, N. Koca and Y. Soyer. 2008 Effect of heat treatment on chlorophyll degradation and color loss in green peas. GIDA 33 (5); 225- 233.

9. Alexander, K.A., L.D. Warnick, C.J. Cripps, P.L. McDonough, Y.T. Grohn, M. Wiedmann, K.E. Reed, K.L. James, Y. Soyer,  and R. Ivanek. 2009. Fecal Shedding, Antimicrobial Resistance, and Serological Response to Salmonella Typhimurium in Calves on Two Dairy Herds in the Northeast U.S. Journal of the American Veterinary Medical Association (JAVMA) 235(6); 739-748.

10. Switt, A. I. M., Y. Soyer, L.D. Warnick, and M. Wiedmann. 2009. Emergence, distribution and molecular and phenotypic characteristics of Salmonella enterica serotype 4,5,12:i:-. Foodborne Pathogens and Disease 6(4);407-415.

11. Davis, M.A., K.N Baker, D.R. Call, L.D. Warnick, Y. Soyer, M. Wiedmann, Y. Gröhn, P.L. McDonough, D.D. Hancock and T.E. Besser. 2009. Multiple locus variable number of tandem repeats typing method for Salmonella enterica serovar Newport. Journal of Clinical. Microbiology 47 (6):1934-1938.

12. Soyer, Y., A. Moreno Switt, M.A. Davis, J. Maurer, P.L. McDonough, D. J. Schoonmaker-Bopp, N. B. Dumas, T. Root, L.D. Warnick, Y.T. Gröhn and M. Wiedmann. 2009 Salmonella 4,5,12:i:-: an emerging Salmonella serotype that represents multiple distinct clones. Journal of Clinical. Microbiology 47 (11):3546-3556.

13. Soyer, Y., R.H. Orsi, L.D.  Rodriguez-Rivera, Q. Sun and M. Wiedmann. 2009. Genome wide evolutionary analyses reveal serotype specific patterns of positive selection in selected Salmonella serotypes. BMC Evolutionary Biology 9: 264- 381. 

14. Soyer Y., S.D. Alcaine, D. Schoonmaker-Bopp, T.P. Root, L.D. Warnick, P. L. McDonough, N.B. Dumas, Y.T. Gröhn and M. Wiedmann. 2010. Pulsed-field Gel Electrophoresis diversity of human and bovine clinical Salmonella isolates. Foodborne Parthogens and Disease 7 (10): 707-717.

15. Davis, M.A., J. Y. Lim, Y. Soyer, H. Harbottle, Y.F. Chang, D. New, L. Orfe, T.E. Besser, and D. R. Call. 2010. Development and validation of a resistance and virulence gene microarray targeting Escherichia coli and Salmonella enterica. Journal of. Microbiology. Methods 82 (1): 36-41.

16. Hoelzer, K.,  Soyer, Y., Rodriguez-Rivera, L.D., Cummings, K.J., McDonough P.L., Schoonmaker-Bopp D.J., Root T.P., Dumas N.B., Warnick L.D., Gröhn Y.T., Wiedmann M. , Baker K.N.K., Besser T.E., Hancock D.D., and Davis M.A. 2010. Prevalence of multidrug resistance is higher among bovine than human Salmonella Newport, Typhimurium and 4,5,12:i:- isolates, but differs by serotype and geographic region in the US. Applied and Environmental Microbiology 76: 5947-5959.

17. Soyer, Y., Richards, J.,  Hoelzer, K., Warnick, L. D., Fortes, E., McDonough, P., Dumas, N.B., Grohn, Y.T.  and M. Wiedmann. 2013. Antimicrobial drug resistance patterns among cattle and human associated Salmonella. Journal of Food Protection, 76 (10): 1676-1688. 

18. Yeni, F., Yavas, S., Soyer, Y. and H. Alpas. 2014. Rapid and standardized methods for detection of foodborne pathogens and mycotoxins on fresh produce. Food Control, 40: 359-267.

19. Gunel, E., G. P. Kilic, E. Bulut, B. Durul, S. Acar, H. Alpas, and Y. Soyer. 2015. Salmonella Surveillance on Fresh Produce in Retails in Turkey. International Journal of Food Microbiology, 199: 72-77.

20. Yeni, F., S. Yavas, H. Alpas and Y. Soyer. 2015. Most Common Foodborne Pathogens and Mycotoxins on Fresh Produce: A review of Recent Outbreaks. Critical Reviews in Food Science and Nutrition (In press, DOI:10.1080/10408398.2013.777021).

21. Kyere, E. O., E. Bulut, M. D. Avşaroğlu, and Y. Soyer. 2015. Molecular Evaluation and antimicrobial susceptibility of Escherichia coli isolates from various food products in Turkey. Food Science and Biotechnology, 24 (3): 1001-1009.

22. Durul, B., S. Acar, E. Bulut, E. O. Kyere, and Y. Soyer. 2015.  Subtyping of Salmonella food isolates suggests overrepresentation of serovar Telaviv in Turkey. Foodborne Pathogens and  Disease (accepted, DOI: 10.1089/fpd.2015.1995 ).

23. Soyer, Y., A. Karaaslan, B. Durul, E. Bulut, S. Acar, İ. Hayoglu, and H. Vardin. 2014. Molecular characterization of Salmonella in pistachio (Pistacia vera) samples from retail markets. Journal of Food, Agriculture and Environment (accepted).

24. Acar, S., E. Bulut, B. Durul, I.Uner, M. Kur, M. D. Avsaroglu, H.A. Kirmaci, Y. O. Tel, F. Y. Zeyrek, and Y. Soyer. 2015. Salmonella Diversity from farm to fork in Turkey. PLOS One (submitted).

Google scholar:  Atif sayisi: 690 h-index: 13

Web of science: Atif sayisi: 368 h-index: 10

Poster ve Sunulu Bildiriler:

1. Y. Soyer, D. Schoonmaker-Bopp, S.D. Alcaine, E.B. Fugett, L.D. Warnick, P. McDonough, N.B. Dumas, Y. Grohn and M. Wiedmann 2006 Subtyping of Salmonella enterica subsp. enterica Serotypes from Human and Cattle Clinical Isolates by Pulsed-Field Gel Electrophoresis and Serotyping. International Conference on "Sustainable development and new technologies for agricultural production in the GAP region" (poster).

2. Y. Soyer, D. Schoonmaker-Bopp, S.D. Alcaine, E.B. Fugett, L.D. Warnick, P. McDonough, N.B. Dumas, Y. Grohn and M. Wiedmann 2006 Subtyping of Salmonella enterica subsp. enterica Serotypes from Human and Cattle Clinical Isolates by Pulsed-Field Gel Electrophoresis and Serotyping. International Association of Food Protection (IAFP) Annual Meeting, Alberta, CANADA (oral presentation).

3. Soyer, Y., R. Orsi, Q. Sun, and M. Wiedmann. 2007. Comparative Genomic Analysis of 5 fully Sequenced Salmonella Genomes. (Abstract publication and poster presentation) 107th Annual Meeting of the American Society of Microbiology, Toronto, Canada.

4. Y. Soyer, A. Moreno, M.A. Davis, J. Maurer, P.L McDonough, L.D. Warnick, Y.T. Grohn and M.Wiedmann. 2008. Different Clones of Salmonella 4,5,12:I:- Isolates Causing Outbreaks in Different Continents (Abstract publication and poster presentation) 108th Annual Meeting of the American Society of Microbiology (ASM), Boston

5. Soyer, Y., R. Orsi, Q. Sun, and M. Wiedmann. 2009. Genome Wide Evolutionary Analyses Reveal Serotypes Specific Patterns of Positive Selection in Selected Salmonella Serotypes (Abstract publication and poster presentation) 3rd American Society of Microbiology (ASM) Conference on Salmonella: Biology, Pathogenesis & Prevention, Aix-en-Provence, France. 

6. Yavaş S., Ögel Z.B., Soyer, Y. 2012. İnsan Bağırsak Mikrobiyotasının Gıdalarla İlişkisi ve İnsan Sağlığına Etkisi. 3. Gıda Güvenliği Kongresi (Abstract publication and poster presentation), İstanbul, Türkiye

7. Y. Soyer, J. Richards, K. Hoelzer, L. D. Warnick, E. Fortes, P. McDonough, N. B. Dumas, Y. Gröhn, and M. Wiedmann . 2012.  Antimicrobial Drug Resistance Patterns among Cattle and Human Associated Salmonella: Are Cattle a Reservoir for Multidrug-resistant Salmonella Linked to Human Disease (Abstract publication and poster presentation). International Association for Food Protection Annual Meeting, Providence, Rhode Island, USA.

8. Cengiz, S., Aktaş Z., Özer, E., Zorlucan, T.F., Kyere, E., Acar Yavaş, S., and  Y. Soyer. 2013. Salmonella surveillance: A survey of packaged chicken meat products and chicken eggs in Ankara, TURKEY. 4th Food Safety Conference, İstanbul, Turkey (Abstract publication and poster presentation) (in Turkish).

9. Durul, B., Yavas, S., Bulut, E., Uner, I., Kur, M., Avsaroglu,.D., Kirmaci, H.A., Tel, O. Y., Zeyrek, F.Y., Dilsiz, N., and Y. Soyer. 2013. Molecular Characterization of Salmonella isolates collected from different sources in Turkey (Abstract publication and poster presentation). 113th Annual Meeting of the American Society of Microbiology, Denver, USA.

10. Durul B., Bulut E., Acar S., Kirmaci H.A., and Y. Soyer . 2013. Multiple Salmonella serovars collected from street foods in Turkey present same allelic  profiles. 4th ASM Conference on Salmonella: The Bacterium, the Host  and the Environment, Boston, Massachusetts, USA.

11. Acar S., E. Bulut, B. Durul, I. Uner, M. Kur, D. Avsaroglu, H.A. Kirmaci, O.Y. Tel, F.Y. Zeyrek, N. Dilsiz, and Y.Soyer. 2013. Various antimicrobial susceptibility profiles obtained from Salmonella from farm/field to fork in Turkey. 4th ASM Conference on Salmonella: The Bacterium, the Host and the Environment, Boston, Massachusetts, USA.

12. Bulut, E., B. Durul, S. Acar, I. Uner, D. Avsaroglu, H.A. Kirmaci, Y.O. Tel, F.Y. Zeyrek, M. Wiedmann and Y. Soyer. 2014. Pulsed-field Gel Electrophoresis (PFGE) Analysis of Temporally Matched Salmonella isolates from human, food and animal sources in southern part of Turkey. 114th Annual Meeting of the American Society of Microbiology, Boston, USA.

13. Oliver, H., Y. Soyer, K. Nightingale, S. McCoy, M. Falk, K. Santiago, L.Bergdoll and K. McNamara. 2014. Food Safety education capacity building programs in Afghanistan. International Association for Food Protection Annual Meeting, Indianapolis, India, USA (Oral presentation by H. Oliver).

14. Acar, S.,  E. Bulut, B. Durul, I. Uner, D. Avsaroglu, H.A. Kirmaci, Y.O. Tel, F.Y. Zeyrek and Y. Soyer. 2014. Antimicrobial Genotyping of Salmonella Isolates with a Comparison of Serotype and Source (Food, Animal and Human) Distribution. International Association for Food Protection Annual Meeting, Indianapolis, India, USA (Oral presentation by S. Acar).

15. S. Acar, E. Bulut, B. Durul, I. Üner, D. Avşaroglu, H.A. Kırmacı, Y.O. Tel, F.Y. Zeyrek and Y. Soyer. 2014. Phenotypic and Genotypic Characterization of Salmonella Isolates from Farm/Field to Fork in Turkey. The 2nd International Congress on Food Technology, Kusadası, Turkey (November 05-07, 2014) (Oral presentation)

Basılı Bildiriler:

1. Soyer, Y. 2003. Pulsed Electric Field Processing of Liquid Foods. International Congress on Information Technology in Agriculture, Food and Environment, Izmir-Turkey (poster presentation).

2. Soyer, Y., J. Huck, K. Nightingale, A. Ho, E. Fortes, M. Wiedmann, and K. J. Boor. 2006. Emerging techniques for assuring farm-to-table food safety. Proceedings, International Conference on "Sustainable development and new technologies for agricultural production in the GAP region". pp.43 - 49.

Düzenlenlediği Çalıştaylar:

“Second International Molecular Methods in Food Microbiology Symposium and Workshop Series”: April 26th-April 27th and April 29th -30th 2010; Harran University, Sanliurfa and Middle East Technical University, Ankara, TURKEY (organizer, instructor).

“Training on Foodborne pathogens: diagnostics, safety, bio-security, molecular typing and food protection”: October 1-2, 2012, METU, Ankara Turkey (organizer, instructor).

“Food Microbiology Workshop for Afghan Government Food Safety Personnel." :July 15-August 3, 2013, METU, Ankara Turkey (organizer, program manager, instructor). This workshop was jointly developed with Purdue University to provide foundation microbiology training to Afghan Ministry of Agriculture and Ministry of Public Health food safety diagnostic staff.  The workshop included lecture and lab education/training components.

Destek Aldığı Projeler:

TUBİTAK 2227- “Second International Molecular Methods in Food Microbiology Symposium and Workshop Series” Adlı Çalıştayı Destekleme

TUBİTAK 2221- Dr. Martin Wiedmann için Konuk Bilim Insanı Desteği

TUBİTAK 2221- Dr. Kendra Nightingale için Konuk Bilim Insanı Desteği

Moleküler Alt Tiplendirme Kapasitesi Kurulması (2012) ODTÜ BAP- 03-14-2012-001 (Yürütücü). (Bütçesi: 36.816,00 TL)

Taze Meyve ve Sebzelerde Yaygın Bulunan Patojelerin Alt Tiplendirilmesi (2012-2013) ODTÜ BAP-08-11-2012-115 (Yürütücü). (Bütçesi: 30 000 TL)

Hayvansal Gıdalarda Yaygın Bulunan Patojenlerin Alt Tiplendirilmesi (2013-2014) ODTÜ BAP- 03-14-2013-001 (Yürütücü). (Bütçesi: 10.000,00 TL)

Çalışmakta Olduğu Projeler:

Şanlıurfa ili ve Civarındaki Klinik İnsan ve Hayvan Vakaları ile Gıdaladaki Salmonella Çeşitliliğininin Moleküler Düzeyde Belirlenmesi (2011-2014).  TUBITAK 3501-111O192 (Yürütücü). (Bütçesi: 242.625 TL)

Plant and Food Biosecurity: A European Network of Excellence (2011-2015). The European Union, Seventh Framework Programme (FP7/2007–2013 – FP7/2007–2011) under Grant Agreement n°261752 (Araştırmacı). (Toplam bütçesi: 3.723963.00 EUR; ODTÜ bütçesi: 411.760.00 EUR)

Çoklu İlaç Dirençli Salmonella İzolatlarındaki Plazmidlerin Çeşitliliği ve İletişim Kabiliyetleri (2014-2017). TUBITAK 114O180 (Yürütücü). (Bütçesi: 342.805 TL)

Sıcak Yemeklerin Raf Ömrünü Uzatmak İçin Buzdolabında Ideal Saklama Koşullarının Belirlenmesi ve Buna Uygun Özel Soğutucu Bölmenin Tasarlanarak Buzdolaplarına Uygulanması (2014-2016).  TÜBİTAK 1505 5130062 (Araştırmacı). 

Food Recovery and Waste Reduction- FoodWard (2014-2016). The European Union, Erasmus+ Programme (Araştırmacı). 

Katıldığı Çalıştaylar:

Workshop on Molecular Evolution provided by Marine Biological Laboratories from July 27th to August 8th, 2008 in Woods Hole, MA.

Üyelikler:

American Society for Microbiology (2006- Present)

International Association for Food Protection (2005- Present)

New York State Association for Food Protection (2005- Present)

Yabancı diller:

İngilizce (A seviyesi)